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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619554
Species: Homo sapiens
RGD Object: Gene
Symbol: CD36
Name: CD36 molecule (CD36 blood group)
Acc ID: CHEBI:17747
Term: bis(2-ethylhexyl) phthalate
Definition: A phthalate ester that is the bis(2-ethylhexyl) ester of benzene-1,2-dicarboxylic acid.
Chemical ID: MESH:D004051
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CD36increases expressionISOCd36 (Mus musculus)6480464CTDDiethylhexyl Phthalate results in increased expression of CD36 mRNAPMID:19245819 PMID:19850644 PMID:30284816 PMID:32325186
CD36multiple interactionsISOCd36 (Mus musculus)6480464CTD[Dietary Sucrose co-treated with Dietary Fats co-treated with bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl] results in increased expression of CD36 mRNA; [Ethanol co-treated with Diethylhexyl Phthalate] results in increased expression of CD36 mRNA; [Tetrachlorodibenzodioxin co-treated with bisphenol A co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Diethylhexyl Phthalate co-treated with Dietary Fats] results in increased expression of CD36 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CD36 mRNA]; PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of CD36 mRNA]PMID:19850644 PMID:23756648 PMID:29718165 PMID:30722647 PMID:32325186
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