GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Crebbp | increases acetylation | ISO | CREBBP (Homo sapiens) | 6480464 | CTD | arsenite results in increased acetylation of CREBBP protein | PMID:33097607 | Crebbp | multiple interactions | ISO | CREBBP (Homo sapiens) | 6480464 | CTD | 3-(4-methylphenylsulfonyl)-2-propenenitrile promotes the reaction [arsenite promotes the reaction [TP53 protein binds to CREBBP protein]]; arsenite inhibits the reaction [G3BP1 protein binds to CREBBP mRNA]; arsenite promotes the reaction [CHUK protein binds to EP300 protein modified form binds to CREBBP protein modified form]; arsenite promotes the reaction [RELA protein binds to CREBBP protein]; arsenite promotes the reaction [TP53 protein binds to CREBBP protein]; arsenite promotes the reaction [TP53 protein binds to EP300 protein binds to CREBBP protein]; arsenite promotes the reaction [TP53 protein binds to EP300 protein modified form binds to CREBBP protein modified form]; CHEK1 protein affects the reaction [arsenite promotes the reaction [TP53 protein binds to EP300 protein modified form binds to CREBBP protein modified form]]; CHUK protein affects the reaction [arsenite promotes the reaction [TP53 protein binds to EP300 protein binds to CREBBP protein]]; CHUK protein affects the reaction [arsenite promotes the reaction [TP53 protein binds to EP300 protein modified form binds to CREBBP protein modified form]]; CHUK protein promotes the reaction [arsenite results in increased acetylation of CREBBP protein]; CREBBP protein affects the reaction [arsenite results in decreased expression of SQSTM1 protein]; CREBBP protein affects the reaction [arsenite results in increased acetylation of TP53 protein]; CREBBP protein affects the reaction [arsenite results in increased expression of and results in increased lipidation of MAP1LC3B protein]; CREBBP protein affects the reaction [arsenite results in increased expression of BECN1 protein]; CREBBP protein affects the reaction [arsenite results in increased expression of DRAM1 protein]; CREBBP protein affects the reaction [arsenite results in increased phosphorylation of and results in increased degradation of CHUK protein]; HSPA9 protein inhibits the reaction [arsenite promotes the reaction [TP53 protein binds to CREBBP protein]]; HSPA9 protein promotes the reaction [3-(4-methylphenylsulfonyl)-2-propenenitrile promotes the reaction [arsenite promotes the reaction [TP53 protein binds to CREBBP protein]]]; HSPA9 protein promotes the reaction [arsenite promotes the reaction [RELA protein binds to CREBBP protein]]; RELA protein inhibits the reaction [arsenite promotes the reaction [TP53 protein binds to CREBBP protein]] | PMID:20199942 PMID:32406909 PMID:33097607 | | ||||||||||||||||||||||
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