GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Crebbp | multiple interactions | EXP | | 6480464 | CTD | Quercetin inhibits the reaction [CREBBP protein binds to CXCL10 promoter]; Quercetin inhibits the reaction [CREBBP protein binds to CXCL2 promoter]; Quercetin inhibits the reaction [TNF protein promotes the reaction [CREBBP protein binds to CXCL10 promoter]]; Quercetin inhibits the reaction [TNF protein promotes the reaction [CREBBP protein binds to CXCL2 promoter]] | PMID:17449583 PMID:21857970 | Crebbp | affects activity | ISO | Crebbp (Rattus norvegicus) | 6480464 | CTD | Quercetin affects the activity of CREBBP modified form | PMID:19423323 | Crebbp | decreases expression | ISO | CREBBP (Homo sapiens) | 6480464 | CTD | Quercetin results in decreased expression of CREBBP protein | PMID:15580028 | Crebbp | increases expression | ISO | CREBBP (Homo sapiens) | 6480464 | CTD | Quercetin results in increased expression of CREBBP mRNA | PMID:14715546 | Crebbp | multiple interactions | ISO | CREBBP (Homo sapiens) | 6480464 | CTD | [Cisplatin co-treated with Quercetin] results in increased expression of CREBBP mRNA | PMID:27514524 | |
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