GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hif1a | multiple interactions | EXP | | 6480464 | CTD | [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of HIF1A protein | PMID:30974164 | Hif1a | increases expression | ISO | Hif1a (Mus musculus) | 6480464 | CTD | chromium hexavalent ion results in increased expression of HIF1A protein | PMID:36739042 | Hif1a | increases expression | ISO | HIF1A (Homo sapiens) | 6480464 | CTD | chromium hexavalent ion results in increased expression of HIF1A mRNA; chromium hexavalent ion results in increased expression of HIF1A protein | PMID:19616015 PMID:23748240 PMID:25448439 | Hif1a | increases stability | ISO | Hif1a (Mus musculus) | 6480464 | CTD | chromium hexavalent ion results in increased stability of HIF1A mRNA | PMID:36739042 | Hif1a | increases stability | ISO | HIF1A (Homo sapiens) | 6480464 | CTD | chromium hexavalent ion results in increased stability of HIF1A protein | PMID:17382205 | Hif1a | multiple interactions | ISO | Hif1a (Mus musculus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of HIF1A protein]; chromium hexavalent ion results in increased expression of and results in decreased methylation of HIF1A mRNA; HIF1A protein affects the reaction [chromium hexavalent ion affects the expression of and results in increased lipidation of MAP1LC3B protein]; HIF1A protein affects the reaction [chromium hexavalent ion results in decreased expression of SQSTM1 protein]; HIF1A protein affects the reaction [chromium hexavalent ion results in decreased expression of TOM20 protein]; HIF1A protein affects the reaction [chromium hexavalent ion results in increased expression of BNIP3 protein]; HIF1A protein affects the reaction [chromium hexavalent ion results in increased phosphorylation of BECN1 protein]; YTHDF2 protein inhibits the reaction [chromium hexavalent ion results in increased expression of HIF1A protein]; YTHDF2 protein inhibits the reaction [chromium hexavalent ion results in increased stability of HIF1A mRNA] | PMID:36739042 | Hif1a | multiple interactions | ISO | HIF1A (Homo sapiens) | 6480464 | CTD | [chromium hexavalent ion co-treated with nickel sulfate] results in increased expression of HIF1A protein; [sodium bichromate results in decreased susceptibility to chromium hexavalent ion] which results in increased expression of HIF1A mRNA; [sodium bichromate results in decreased susceptibility to chromium hexavalent ion] which results in increased expression of HIF1A protein; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased stability of HIF1A protein]; chromium hexavalent ion inhibits the reaction [Nickel results in increased stability of and results in increased expression of HIF1A protein]; chromium hexavalent ion results in increased expression of and affects the localization of HIF1A protein; Luteolin inhibits the reaction [chromium hexavalent ion results in increased expression of HIF1A mRNA]; Luteolin inhibits the reaction [chromium hexavalent ion results in increased expression of HIF1A protein]; MIR143 inhibits the reaction [chromium hexavalent ion results in increased expression of HIF1A protein]; STAT1 protein affects the reaction [chromium hexavalent ion inhibits the reaction [Nickel results in increased stability of and results in increased expression of HIF1A protein]] | PMID:17382205 PMID:19403854 PMID:23748240 PMID:25448439 PMID:31152816 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |