GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Slc30a1 | decreases uptake | ISO | Slc30a1 (Mus musculus) | 6480464 | CTD | SLC30A1 protein results in decreased uptake of Cadmium | PMID:19288494 | Slc30a1 | increases expression | ISO | Slc30a1 (Mus musculus) | 6480464 | CTD | Cadmium results in increased expression of SLC30A1 | PMID:19288494 | Slc30a1 | increases expression | ISO | SLC30A1 (Homo sapiens) | 6480464 | CTD | Cadmium results in increased expression of SLC30A1 mRNA; Cadmium results in increased expression of SLC30A1 protein | PMID:14568174 PMID:21120746 | Slc30a1 | multiple interactions | ISO | Slc30a1 (Mus musculus) | 6480464 | CTD | [ABCG2 gene mutant form results in increased susceptibility to [Cadmium Chloride results in increased abundance of Cadmium]] which results in decreased expression of SLC30A1 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC30A1 mRNA; SLC30A1 inhibits the reaction [Cadmium results in increased expression of and results in increased secretion of CLU protein] | PMID:19288494 PMID:37325564 PMID:37941438 | Slc30a1 | multiple interactions | ISO | SLC30A1 (Homo sapiens) | 6480464 | CTD | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC30A1 mRNA; Cadmium results in increased expression of and affects the localization of SLC30A1 protein | PMID:19900532 PMID:29741670 PMID:31738976 PMID:35301059 | |
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