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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61913
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gas6
Name: growth arrest specific 6
Acc ID: CHEBI:5132
Term: flutamide
Definition: A (trifluoromethyl)benzene that has formula C11H11F3N2O3.
Chemical ID: MESH:D005485
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gas6decreases expressionEXP 6480464CTDFlutamide results in decreased expression of GAS6 mRNAPMID:24136188
Gas6multiple interactionsISOGAS6 (Homo sapiens)6480464CTDFlutamide inhibits the reaction [Dihydrotestosterone results in increased expression of GAS6 mRNA]; Flutamide inhibits the reaction [Testosterone inhibits the reaction [Phosphates results in decreased expression of GAS6 mRNA]]; Flutamide inhibits the reaction [Testosterone inhibits the reaction [Phosphates results in decreased expression of GAS6 protein]]PMID:20048160
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