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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61912
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc6a6
Name: solute carrier family 6 member 6
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionISORGD:690046480464CTDEstradiol results in increased expression of SLC6A6 mRNA, Estradiol results in increased expression of TAUT mRNA

PMID:15223131, PMID:19619570, PMID:23019147
multiple interactionsISORGD:690046480464CTD[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of SLC6A6 mRNA, Estradiol promotes the reaction [ESR2 protein affects the expression of SLC6A6 mRNA]

PMID:19619570, PMID:20404318
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.