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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61909
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1h3
Name: nuclear receptor subfamily 1, group H, member 3
Acc ID: CHEBI:28077
Term: rifampicin
Definition: A member of the class of rifamycins that is a a semisynthetic antibiotic derived from Amycolatopsis rifamycinica (previously known as Amycolatopsis mediterranei and Streptomyces mediterranei).
Chemical ID: MESH:D012293
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1h3multiple interactionsISONR1H3 (Homo sapiens)6480464CTDNR1H3 mutant form inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]PMID:23732298
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