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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61888
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Map2k2
Name: mitogen activated protein kinase kinase 2
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map2k2affects expressionEXP 6480464CTDpirinixic acid affects the expression of MAP2K2 mRNAPMID:19483382
Map2k2increases expressionISOMap2k2 (Mus musculus)6480464CTDpirinixic acid results in increased expression of MAP2K2 mRNAPMID:23811191
Map2k2multiple interactionsISOMap2k2 (Mus musculus)6480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of MAP2K2 mRNAPMID:19710929
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