GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp9 | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of CASP9 mRNA; bisphenol A results in decreased expression of CASP9 protein | PMID:25181051 PMID:27189055 | Casp9 | increases activity | EXP | | 6480464 | CTD | bisphenol A results in increased activity of CASP9 protein | PMID:25461564 | Casp9 | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of CASP9 mRNA; bisphenol A results in increased expression of CASP9 protein | PMID:17322771 PMID:25461564 PMID:27296223 PMID:27539358 PMID:31129395 PMID:32172062 PMID:32428650 PMID:32810514 | Casp9 | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A co-treated with naringin] results in decreased expression of CASP9 protein; [bisphenol A co-treated with tributyltin] results in increased expression of CASP9 mRNA; [NG-Nitroarginine Methyl Ester co-treated with bisphenol A co-treated with naringin] results in decreased expression of CASP9 protein; [NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of CASP9 protein; bisphenol A promotes the reaction [Genistein results in increased cleavage of CASP9 protein]; bisphenol A promotes the reaction [NG-Nitroarginine Methyl Ester results in increased expression of CASP9 protein]; bisphenol A results in increased expression of and results in increased cleavage of CASP9 protein; naringin inhibits the reaction [[NG-Nitroarginine Methyl Ester co-treated with bisphenol A] results in increased expression of CASP9 protein]; naringin inhibits the reaction [bisphenol A results in increased expression of CASP9 protein]; NG-Nitroarginine Methyl Ester inhibits the reaction [bisphenol A results in increased expression of CASP9 protein] | PMID:24884420 PMID:25461564 PMID:31129395 PMID:32172062 PMID:32428650 PMID:32810514 | Casp9 | affects expression | ISO | Casp9 (Mus musculus) | 6480464 | CTD | bisphenol A affects the expression of CASP9 protein | PMID:23900028 | Casp9 | decreases expression | ISO | Casp9 (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased expression of CASP9 mRNA | PMID:29161229 | Casp9 | decreases expression | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased expression of CASP9 mRNA | PMID:36982678 | Casp9 | increases activity | ISO | Casp9 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased activity of CASP9 protein | PMID:31387175 | Casp9 | increases activity | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased activity of CASP9 protein | PMID:30036487 PMID:30841469 PMID:33916708 PMID:34664771 | Casp9 | increases cleavage | ISO | Casp9 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased cleavage of CASP9 protein | PMID:36858637 | Casp9 | increases expression | ISO | Casp9 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of CASP9 mRNA; bisphenol A results in increased expression of CASP9 protein | PMID:31201698 PMID:31387175 PMID:32488702 PMID:33221593 | Casp9 | increases expression | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased expression of CASP9 mRNA; bisphenol A results in increased expression of CASP9 protein | PMID:21277958 PMID:30841469 PMID:31400064 | Casp9 | multiple interactions | ISO | Casp9 (Mus musculus) | 6480464 | CTD | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of CASP9 protein; Drugs, Chinese Herbal inhibits the reaction [bisphenol A results in increased expression of CASP9 protein]; VDAC1 promotes the reaction [bisphenol A results in increased cleavage of CASP9 protein] | PMID:32488702 PMID:35739755 PMID:36858637 | Casp9 | multiple interactions | ISO | CASP9 (Homo sapiens) | 6480464 | CTD | [naringenin co-treated with bisphenol A] results in increased expression of CASP9 mRNA; [naringenin metabolite co-treated with bisphenol A] results in increased expression of CASP9 mRNA | PMID:36235125 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |