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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61867
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp9
Name: caspase 9
Acc ID: CHEBI:63718
Term: tenofovir disoproxil fumarate
Definition: A fumarate salt prepared from equimolar amounts of tenofovir disoproxil and fumaric acid. It is used in combination therapy for the treatment of HIV infection.
Chemical ID: MESH:D000068698
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp9increases expressionEXP 6480464CTDTenofovir results in increased expression of CASP9 proteinPMID:33146023
Casp9multiple interactionsEXP 6480464CTDMelatonin inhibits the reaction [Tenofovir results in increased expression of CASP9 protein]PMID:33146023
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