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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61867
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp9
Name: caspase 9
Acc ID: CHEBI:29014
Term: cordycepin
Definition: A 3'-deoxyribonucleoside that has formula C10H13N5O3.
Chemical ID: MESH:C058120
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp9multiple interactionsEXP 6480464CTDcordycepin inhibits the reaction [Calcium Chloride results in increased cleavage of CASP9 protein]; cordycepin inhibits the reaction [Lidocaine results in increased expression of CASP9 mRNA]; cordycepin inhibits the reaction [Lidocaine results in increased expression of CASP9 protein]PMID:29382532 PMID:36731150
Casp9increases activityISOCASP9 (Homo sapiens)6480464CTDcordycepin results in increased activity of CASP9 proteinPMID:21310227 PMID:21933677
Casp9increases cleavageISOCASP9 (Homo sapiens)6480464CTDcordycepin results in increased cleavage of CASP9 proteinPMID:21196698 PMID:32451092 PMID:32730909 PMID:35732609
Casp9increases expressionISOCASP9 (Homo sapiens)6480464CTDcordycepin results in increased expression of CASP9 mRNAPMID:28987792 PMID:32730909
Casp9multiple interactionsISOCASP9 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [cordycepin results in increased activity of CASP9 protein]PMID:21310227
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