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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61856
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gabra2
Name: gamma-aminobutyric acid type A receptor subunit alpha 2
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gabra2decreases expressionEXP 6480464CTDEthanol results in decreased expression of GABRA2 mRNAPMID:1711815
Gabra2increases expressionEXP 6480464CTDEthanol deficiency results in increased expression of GABRA2 mRNA; Ethanol deficiency results in increased expression of GABRA2 proteinPMID:14684873 PMID:17403139
Gabra2multiple interactionsEXP 6480464CTDDiazepam inhibits the reaction [Ethanol deficiency results in increased expression of GABRA2 mRNA]PMID:14684873
Gabra2increases expressionISOGabra2 (Mus musculus)6480464CTDEthanol results in increased expression of GABRA2 mRNAPMID:30319688
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