Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


RGD ID: 61846
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Psma4
Name: proteasome subunit alpha 4
Acc ID: CHEBI:4903
Term: 17alpha-ethynylestradiol
Definition: A 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration.
Chemical ID: MESH:D004997
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionEXP 6480464CTDEthinyl Estradiol results in decreased expression of PSMA4 mRNA

increases expressionEXP 6480464CTDEthinyl Estradiol results in increased expression of PSMA4 mRNA

PMID:16174780, PMID:24096037
affects expressionISORGD:621386480464CTDEthinyl Estradiol affects the expression of PSMA4 mRNA

increases expressionISORGD:621386480464CTDEthinyl Estradiol results in increased expression of PSMA4 mRNA

PMID:16174780, PMID:17942748, PMID:24096037
multiple interactionsISORGD:621386480464CTD[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PSMA4 mRNA

Go Back to source page   Continue to Ontology report


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.