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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61821
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgfbr3
Name: transforming growth factor beta receptor 3
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfbr3multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of TGFBR3 mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in decreased expression of TGFBR3 protein; [Phenobarbital co-treated with Diethylnitrosamine] results in decreased expression of TGFBR3 mRNAPMID:8001232 PMID:8565130
Tgfbr3decreases expressionISOTgfbr3 (Mus musculus)6480464CTDPhenobarbital results in decreased expression of TGFBR3 mRNAPMID:19482888
Tgfbr3multiple interactionsISOTgfbr3 (Mus musculus)6480464CTDNR1I3 protein affects the reaction [Phenobarbital results in decreased expression of TGFBR3 mRNA]PMID:19482888
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