GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Col1a1 | increases expression | EXP | | 6480464 | CTD | Dimethylnitrosamine results in increased expression of COL1A1 mRNA | PMID:15571005 PMID:15723089 PMID:16169303 PMID:16570917 PMID:25380136 | Col1a1 | multiple interactions | EXP | | 6480464 | CTD | 2-phenyl-4-(3-pyridin-2-yl-1H-pyrazol-4-yl)pyridine inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA]; 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA]; [Dietary Fats co-treated with Dimethylnitrosamine] results in increased expression of COL1A1 mRNA; [Silybin co-treated with Phosphatidylcholines co-treated with Vitamin E] inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA]; GJB1 protein affects the reaction [[Dietary Fats co-treated with Dimethylnitrosamine] results in increased expression of COL1A1 mRNA]; pirfenidone inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A1 mRNA] | PMID:15571005 PMID:15723089 PMID:16169303 PMID:16570917 PMID:32833043 | | ||||||||||||||||||||||
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