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GENE - TERM ANNOTATION REPORT

RGD ID: 61800
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Htr2a
Name: 5-hydroxytryptamine receptor 2A
Acc ID: DOID:10933
Term: obsessive-compulsive disorder
Definition: An anxiety disorder that involves unwanted and repeated thoughts, feelings, ideas, sensations (obsessions), or behaviors that make them feel driven to do something (compulsions). (DO)
Definition Source(s): https://www.nimh.nih.gov/health/topics/obsessive-compulsive-disorder-ocd/index.shtml "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Htr2asusceptibilityISOHTR2A (Homo sapiens)7240710OMIM  
Htr2a ISOHTR2A (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanismPMID:19644229
Htr2a ISOHTR2A (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Obsessive-compulsive disorder, susceptibility toPMID:12476319 PMID:15364038 PMID:9635956
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