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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3952
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vcam1
Name: vascular cell adhesion molecule 1
Acc ID: CHEBI:53063
Term: 2,4,6-trinitrobenzenesulfonic acid
Definition: The arenesulfonic acid that is benzenesulfonic acid with three nitro substituents in the 2-, 4- and 6-positions.
Chemical ID: MESH:D014302
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vcam1increases expressionEXP 6480464CTDTrinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA; Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 proteinPMID:22029500 PMID:30503585
Vcam1multiple interactionsEXP 6480464CTDHydroxamic Acids analog promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA]; Resveratrol inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 protein]; Sulfur Dioxide inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNA]PMID:22029500 PMID:30503585
Vcam1increases expressionISOVcam1 (Mus musculus)6480464CTDTrinitrobenzenesulfonic Acid results in increased expression of VCAM1 mRNAPMID:17982090
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