Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3952
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vcam1
Name: vascular cell adhesion molecule 1
Acc ID: CHEBI:34317
Term: 3,3',4,4',5-pentachlorobiphenyl
Definition: A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.
Chemical ID: MESH:C023035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vcam1decreases expressionEXP 6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of VCAM1 mRNAPMID:23196670
Vcam1affects expressionISOVcam1 (Mus musculus)6480464CTD3,4,5,3',4'-pentachlorobiphenyl affects the expression of VCAM1 mRNAPMID:37080397
Vcam1decreases expressionISOVCAM1 (Homo sapiens)6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of VCAM1 mRNAPMID:22262711
Vcam1increases expressionISOVcam1 (Mus musculus)6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA; 3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 proteinPMID:20406653 PMID:24709675
Vcam1increases expressionISOVCAM1 (Homo sapiens)6480464CTD3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNAPMID:26519613
Vcam1multiple interactionsISOVcam1 (Mus musculus)6480464CTDCAV1 gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein]PMID:20406653 PMID:24709675
Go Back to source page   Continue to Ontology report