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GENE - TERM ANNOTATION REPORT

RGD ID: 3951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vav1
Name: vav guanine nucleotide exchange factor 1
Acc ID: GO:0005088
Term: Ras guanyl-nucleotide exchange factor activity
Definition: Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ras superfamily. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
Definition Source(s): GOC:mah
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
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