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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3932
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ucp2
Name: uncoupling protein 2
Acc ID: CHEBI:16598
Term: DDE
Definition: A chlorophenylethylene that is ethylene substituted by two 4-chlorophenyl groups at position 1 and two chlorine atoms at position 2.
Chemical ID: MESH:D003633
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ucp2increases expressionEXP 6480464CTDDichlorodiphenyl Dichloroethylene results in increased expression of UCP2 mRNA; Dichlorodiphenyl Dichloroethylene results in increased expression of UCP2 proteinPMID:31022254
Ucp2multiple interactionsEXP 6480464CTDDichlorodiphenyl Dichloroethylene promotes the reaction [Dietary Fats results in increased expression of UCP2 mRNA]; Dichlorodiphenyl Dichloroethylene promotes the reaction [Dietary Fats results in increased expression of UCP2 protein]; Dietary Fats inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of UCP2 mRNA]; Dietary Fats inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of UCP2 protein]PMID:31022254
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