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GENE - TERM ANNOTATION REPORT

RGD ID: 3918
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tub
Name: TUB bipartite transcription factor
Acc ID: GO:0006910
Term: phagocytosis, recognition
Definition: The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.
Definition Source(s): GOC:curators, ISBN:0781735149
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tubacts_upstream_of_or_withinISOTub (Mus musculus)1624291RGDMGI:1861349 PMID:19837063 PMID:20978472

PMID:19837063 PMID:20978472
Tubinvolved_inIEAUniProtKB:P50586 or ensembl:ENSMUSP000000333411600115EnsemblGO_REF:0000107

GO_REF:0000107
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