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GENE - TERM ANNOTATION REPORT

RGD ID: 3916
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ttr
Name: transthyretin
Acc ID: DOID:9003163
Term: Heart Block
Definition: Impaired conduction of cardiac impulse that can occur anywhere along the conduction pathway, such as between the SINOATRIAL NODE and the right atrium (SA block) or between atria and ventricles (AV block). Heart blocks can be classified by the duration, frequency, or completeness of conduction block. Reversibility depends on the degree of structural or functional defects.
Definition Source(s): MESH:D006327
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ttr ISOTTR (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Conduction disorder of the heartPMID:10439123 PMID:25741868 PMID:26467025 PMID:28492532 PMID:29875424 PMID:31371117 PMID:35903975
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