GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3911
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tshr
Name: thyroid stimulating hormone receptor
Acc ID: CHEBI:27638
Term: cobalt atom
Definition: A cobalt group element atom that has atomic number 27.
Chemical ID: MESH:D003035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7370216480464CTD[Cobalt binds to dipyrido(3,2-a-2',3'-c)phenazine binds to N-(2-hydroxybenzyl)glycine analog] which binds to and affects the localization of and results in increased cleavage of TSHR protein

TSHR protein results in increased susceptibility to [Cobalt binds to dipyrido(3,2-a-2',3'-c)phenazine binds to N-(2-hydroxybenzyl)glycine analog]

PMID:21072367
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.