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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3910
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tshb
Name: thyroid stimulating hormone subunit beta
Acc ID: CHEBI:16598
Term: DDE
Definition: A chlorophenylethylene that is ethylene substituted by two 4-chlorophenyl groups at position 1 and two chlorine atoms at position 2.
Chemical ID: MESH:D003633
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tshbmultiple interactionsEXP 6480464CTD[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of TSHB proteinPMID:24878560
Tshbmultiple interactionsISOTSHB (Homo sapiens)6480464CTDDichlorodiphenyl Dichloroethylene affects the expression of and affects the secretion of TSHB proteinPMID:19750101
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