GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tp53 | multiple interactions | EXP | | 6480464 | CTD | ADORA2A mutant form inhibits the reaction [cordycepin results in increased phosphorylation of and results in increased expression of TP53 protein]; cordycepin promotes the reaction [Etoposide results in increased expression of TP53 protein]; cordycepin results in increased phosphorylation of and results in increased expression of TP53 protein; TP53 mutant form inhibits the reaction [cordycepin results in increased cleavage of CASP7 protein]; TP53 mutant form inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein]; ZM 241385 inhibits the reaction [cordycepin results in increased phosphorylation of and results in increased expression of TP53 protein] | PMID:23690541 PMID:24704558 | Tp53 | affects expression | ISO | TP53 (Homo sapiens) | 6480464 | CTD | cordycepin affects the expression of TP53 mRNA | PMID:36881089 | Tp53 | increases expression | ISO | TP53 (Homo sapiens) | 6480464 | CTD | cordycepin results in increased expression of TP53 mRNA | PMID:28987792 | Tp53 | increases phosphorylation | ISO | Trp53 (Mus musculus) | 6480464 | CTD | cordycepin results in increased phosphorylation of TRP53 protein | PMID:26303320 | Tp53 | multiple interactions | ISO | TP53 (Homo sapiens) | 6480464 | CTD | [Cisplatin co-treated with cordycepin] results in increased phosphorylation of TP53 protein | PMID:33520990 | | ||||||||||||||||||||||
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