GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases secretion | EXP | | 6480464 | CTD | Famotidine results in increased secretion of TNF protein | PMID:17698507 | Tnf | multiple interactions | EXP | | 6480464 | CTD | Famotidine inhibits the reaction [Ethanol results in increased expression of TNF protein]; Famotidine inhibits the reaction [Ethanol results in increased secretion of TNF protein]; Famotidine inhibits the reaction [Indomethacin results in increased expression of TNF mRNA] | PMID:17603938 PMID:27474069 PMID:27645307 | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]] | PMID:19277450 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | Famotidine inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in increased expression of TNF protein]]; Famotidine inhibits the reaction [Histamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]] | PMID:11752121 PMID:12538815 | |
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