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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:135888
Term: pimecrolimus
Definition: null
Chemical ID: MESH:C117268
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfdecreases expressionISOTNF (Homo sapiens)6480464CTDpimecrolimus results in decreased expression of TNF proteinPMID:12296857
Tnfincreases secretionISOTnf (Mus musculus)6480464CTDpimecrolimus results in increased secretion of TNF proteinPMID:15086553
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