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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3850
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tsc22d1
Name: TSC22 domain family, member 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tsc22d1affects expressionEXP 6480464CTDbisphenol A affects the expression of TSC22D1 mRNAPMID:30903817
Tsc22d1increases expressionEXP 6480464CTDbisphenol A results in increased expression of TSC22D1 mRNAPMID:25181051 PMID:30816183 PMID:32145629 PMID:34947998
Tsc22d1affects methylationISOTSC22D1 (Homo sapiens)6480464CTDbisphenol A affects the methylation of TSC22D1 genePMID:31601247
Tsc22d1affects methylationISOTsc22d1 (Mus musculus)6480464CTDbisphenol A affects the methylation of TSC22D1 promoterPMID:27334623
Tsc22d1decreases expressionISOTSC22D1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of TSC22D1 mRNAPMID:19371625
Tsc22d1increases expressionISOTSC22D1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of TSC22D1 mRNAPMID:29275510
Tsc22d1increases expressionISOTsc22d1 (Mus musculus)6480464CTDbisphenol A results in increased expression of TSC22D1 mRNAPMID:26063408
Tsc22d1multiple interactionsISOTSC22D1 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of TSC22D1 genePMID:31601247
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