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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3848
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tg
Name: thyroglobulin
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgdecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of TG mRNAPMID:25181051 PMID:30816183 PMID:32528016
Tgincreases expressionEXP 6480464CTDbisphenol A results in increased expression of TG mRNAPMID:23238275 PMID:26827900 PMID:34947998
Tgincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of TG genePMID:28505145
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