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GENE - TERM ANNOTATION REPORT

RGD ID: 3825
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tbxa2r
Name: thromboxane A2 receptor
Acc ID: GO:0007189
Term: adenylate cyclase-activating G protein-coupled receptor signaling pathway
Definition: A G protein-coupled receptor signaling pathway in which the signal is transmitted via the activation of adenylyl cyclase activity which results in an increase in the intracellular concentration of cyclic AMP (cAMP). This pathway is negatively regulated by phosphodiesterase, which cleaves cAMP and terminates the signaling.
Definition Source(s): GOC:dph, GOC:mah, GOC:signaling, GOC:tb, ISBN:0815316194
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tbxa2rinvolved_inIBAMGI:97793 or MGI:97794 or MGI:99535 or PANTHER:PTN000933518 or UniProtKB:P431191600115GO_CentralGO_REF:0000033

GO_REF:0000033
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