GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Syp | decreases expression | EXP | | 6480464 | CTD | lead acetate results in decreased expression of SYP protein | PMID:17047031 PMID:20375082 | Syp | increases expression | EXP | | 6480464 | CTD | lead acetate results in increased expression of SYP protein | PMID:27984133 | Syp | multiple interactions | EXP | | 6480464 | CTD | BDNF protein inhibits the reaction [lead acetate results in decreased expression of SYP protein] | PMID:20375082 | Syp | decreases expression | ISO | Syp (Mus musculus) | 6480464 | CTD | lead acetate results in decreased expression of SYP protein | PMID:27771255 | Syp | multiple interactions | ISO | Syp (Mus musculus) | 6480464 | CTD | [lead acetate results in increased abundance of Lead] which results in decreased expression of SYP mRNA; [lead acetate results in increased abundance of Lead] which results in decreased expression of SYP protein | PMID:26660114 | Syp | multiple interactions | ISO | SYP (Homo sapiens) | 6480464 | CTD | [[lead acetate results in increased abundance of Lead] which co-treated with APP protein modified form] results in decreased expression of SYP protein; [lead acetate results in increased abundance of Lead] promotes the reaction [[APP protein co-treated with APP protein modified form] results in decreased expression of SYP protein]; [lead acetate results in increased abundance of Lead] promotes the reaction [APP protein results in decreased expression of SYP protein]; [lead acetate results in increased abundance of Lead] which results in decreased expression of SYP protein | PMID:31843630 | |
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