Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3802
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Syp
Name: synaptophysin
Acc ID: CHEBI:31767
Term: lead diacetate
Definition: A lead coordination entity in which a central lead(2+) atom is coordinated to two acetate ions.
Chemical ID: MESH:C008261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sypdecreases expressionEXP 6480464CTDlead acetate results in decreased expression of SYP proteinPMID:17047031 PMID:20375082
Sypincreases expressionEXP 6480464CTDlead acetate results in increased expression of SYP proteinPMID:27984133
Sypmultiple interactionsEXP 6480464CTDBDNF protein inhibits the reaction [lead acetate results in decreased expression of SYP protein]PMID:20375082
Sypdecreases expressionISOSyp (Mus musculus)6480464CTDlead acetate results in decreased expression of SYP proteinPMID:27771255
Sypmultiple interactionsISOSyp (Mus musculus)6480464CTD[lead acetate results in increased abundance of Lead] which results in decreased expression of SYP mRNA; [lead acetate results in increased abundance of Lead] which results in decreased expression of SYP proteinPMID:26660114
Sypmultiple interactionsISOSYP (Homo sapiens)6480464CTD[[lead acetate results in increased abundance of Lead] which co-treated with APP protein modified form] results in decreased expression of SYP protein; [lead acetate results in increased abundance of Lead] promotes the reaction [[APP protein co-treated with APP protein modified form] results in decreased expression of SYP protein]; [lead acetate results in increased abundance of Lead] promotes the reaction [APP protein results in decreased expression of SYP protein]; [lead acetate results in increased abundance of Lead] which results in decreased expression of SYP proteinPMID:31843630
Go Back to source page   Continue to Ontology report