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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3787
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc9
Name: ATP binding cassette subfamily C member 9
Acc ID: CHEBI:15866
Term: 2-deoxy-D-glucose
Definition: A deoxyglucose that is D-glucose in which the hydroxy group at position 2 has been replaced by a hydrogen. It is an antimetabolite of glucose with antiviral activity, which acts by inhibiting the glycosylation of glycoproteins and glycolipids. Used as an antiherpes agent.
Chemical ID: MESH:D003847
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc9multiple interactionsISOAbcc9 (Mus musculus)6480464CTD[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]; Glyburide inhibits the reaction [[Oligomycins co-treated with Deoxyglucose] results in increased activity of [KCNJ11 protein binds to ABCC9 protein]]PMID:28842488
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