GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Stat1 | decreases expression | ISO | STAT1 (Homo sapiens) | 6480464 | CTD | Quercetin metabolite results in decreased expression of STAT1 mRNA; Quercetin results in decreased expression of STAT1 mRNA | PMID:15309432 PMID:21632981 PMID:36982678 | Stat1 | decreases phosphorylation | ISO | STAT1 (Homo sapiens) | 6480464 | CTD | Quercetin results in decreased phosphorylation of STAT1 protein | PMID:16077199 | Stat1 | multiple interactions | ISO | STAT1 (Homo sapiens) | 6480464 | CTD | Quercetin inhibits the reaction [STAT1 protein modified form binds to TRADD protein] | PMID:16077199 | Stat1 | multiple interactions | ISO | Stat1 (Mus musculus) | 6480464 | CTD | Quercetin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein]; Quercetin inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]; Quercetin inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of STAT1 protein alternative form]; Quercetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of STAT1 protein]; Quercetin inhibits the reaction [nickel sulfate results in increased phosphorylation of STAT1 protein] | PMID:16171798 PMID:18274639 PMID:20060843 PMID:24040572 PMID:25957741 | |
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