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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3732
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sod2
Name: superoxide dismutase 2
Acc ID: CHEBI:48958
Term: 1,1'-azobis(N,N-dimethylformamide)
Definition: A monoazo compound that has formula C6H12N4O2.
Chemical ID: MESH:D003958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod2increases expressionISOSOD2 (Homo sapiens)6480464CTDDiamide results in increased expression of SOD2 mRNAPMID:8760145
Sod2multiple interactionsISOSOD2 (Homo sapiens)6480464CTDDiamide inhibits the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Diamide inhibits the reaction [IL1A protein results in increased expression of SOD2 protein]; Diamide inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Diamide inhibits the reaction [TNF protein results in increased expression of SOD2 protein]PMID:7476933
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