GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sod1 | decreases expression | ISO | Sod1 (Mus musculus) | 6480464 | CTD | perfluorooctanoic acid results in decreased expression of SOD1 mRNA | PMID:21712084 | Sod1 | increases expression | ISO | Sod1 (Mus musculus) | 6480464 | CTD | perfluorooctanoic acid results in increased expression of SOD1 mRNA | PMID:32578922 | Sod1 | multiple interactions | ISO | Sod1 (Mus musculus) | 6480464 | CTD | 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [perfluorooctanoic acid results in increased expression of SOD1 mRNA]; 4-phenylbutyric acid inhibits the reaction [perfluorooctanoic acid results in increased expression of SOD1 mRNA]; 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine inhibits the reaction [perfluorooctanoic acid results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [perfluorooctanoic acid results in increased expression of SOD1 mRNA] | PMID:32578922 | | ||||||||||||||||||||||
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