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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3682
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc10a2
Name: solute carrier family 10 member 2
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc10a2affects expressionISOSlc10a2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of SLC10A2 mRNAPMID:21570461 PMID:26377647 PMID:28922406
Slc10a2decreases expressionISOSlc10a2 (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of SLC10A2 mRNAPMID:19770486
Slc10a2multiple interactionsISOSlc10a2 (Mus musculus)6480464CTD[TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of SLC10A2 mRNAPMID:25975270
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