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GENE - TERM ANNOTATION REPORT

RGD ID: 3673
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Shh
Name: sonic hedgehog signaling molecule
Acc ID: GO:0014706
Term: striated muscle tissue development
Definition: The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells.
Definition Source(s): CL:0000737, GOC:dph, GOC:mtg_muscle
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Shhacts_upstream_of_or_withinISOShh (Mus musculus)1624291RGDMGI:1861186 PMID:11171399

PMID:11171399
Shhinvolved_inIEAUniProtKB:Q62226 or ensembl:ENSMUSP000000027081600115EnsemblGO_REF:0000107

GO_REF:0000107
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