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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3666
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sftpc
Name: surfactant protein C
Acc ID: CHEBI:7590
Term: nitrofen
Definition: An organic molecular entity that has formula C12H7Cl2NO3.
Chemical ID: MESH:C007350
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sftpcdecreases expressionEXP 6480464CTDnitrofen results in decreased expression of SFTPC mRNA; nitrofen results in decreased expression of SFTPC proteinPMID:10751355 PMID:11057544 PMID:11076806 PMID:11588001 PMID:28188034 PMID:31843527 PMID:34502408
Sftpcincreases expressionEXP 6480464CTDnitrofen results in increased expression of SFTPC mRNAPMID:12904592 PMID:15764645 PMID:33484710
Sftpcmultiple interactionsEXP 6480464CTDFOXA2 protein inhibits the reaction [nitrofen results in decreased expression of SFTPC protein]; Vitamin A inhibits the reaction [nitrofen results in decreased expression of SFTPC mRNA]PMID:11588001 PMID:31843527
Sftpcdecreases expressionISOSftpc (Mus musculus)6480464CTDnitrofen results in decreased expression of SFTPC mRNAPMID:12194114
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