GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rps6 | decreases phosphorylation | EXP | | 6480464 | CTD | resveratrol results in decreased phosphorylation of RPS6 protein | PMID:20332614 | Rps6 | multiple interactions | EXP | | 6480464 | CTD | [Resveratrol co-treated with Sirolimus] results in decreased phosphorylation of RPS6 protein; dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [Pilocarpine results in increased phosphorylation of RPS6 protein]]; Resveratrol inhibits the reaction [Glucose results in increased phosphorylation of RPS6 protein]; Resveratrol inhibits the reaction [Pilocarpine results in increased phosphorylation of RPS6 protein] | PMID:20332614 PMID:23211629 PMID:24304514 | Rps6 | decreases activity | ISO | RPS6 (Homo sapiens) | 6480464 | CTD | resveratrol results in decreased activity of RPS6 protein | PMID:26189302 | Rps6 | decreases expression | ISO | RPS6 (Homo sapiens) | 6480464 | CTD | resveratrol results in decreased expression of RPS6 protein | PMID:17534123 | Rps6 | decreases phosphorylation | ISO | RPS6 (Homo sapiens) | 6480464 | CTD | resveratrol results in decreased phosphorylation of RPS6 protein | PMID:19471118 PMID:19827268 PMID:20080969 PMID:20097879 PMID:23363784 PMID:25311616 | Rps6 | multiple interactions | ISO | RPS6 (Homo sapiens) | 6480464 | CTD | [[resveratrol results in increased activity of SIRT1 protein] which results in decreased activity of MTOR protein] which results in decreased phosphorylation of RPS6 protein; [resveratrol co-treated with Sirolimus] results in decreased phosphorylation of RPS6 protein; [resveratrol results in decreased activity of RPS6KB1 protein] which results in decreased phosphorylation of RPS6 protein; [resveratrol results in increased activity of SIRT1 protein] which results in decreased phosphorylation of RPS6 protein; resveratrol inhibits the reaction [IGF1 protein results in increased phosphorylation of RPS6 protein]; resveratrol results in decreased expression of and results in decreased phosphorylation of RPS6 protein; TSC2 gene mutant form promotes the reaction [[resveratrol co-treated with Sirolimus] results in decreased phosphorylation of RPS6 protein]; TSC2 protein promotes the reaction [[[resveratrol results in increased activity of SIRT1 protein] which results in decreased activity of MTOR protein] which results in decreased phosphorylation of RPS6 protein] | PMID:15297429 PMID:17554206 PMID:20169165 PMID:21544240 PMID:24304514 | Rps6 | multiple interactions | ISO | Rps6 (Mus musculus) | 6480464 | CTD | [resveratrol co-treated with Sirolimus] results in decreased phosphorylation of RPS6 protein; resveratrol inhibits the reaction [TNF protein results in increased phosphorylation of RPS6 protein] | PMID:22069489 PMID:24304514 | | ||||||||||||||||||||||
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