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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3541
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rbl2
Name: RB transcriptional corepressor like 2
Acc ID: CHEBI:16240
Term: hydrogen peroxide
Definition: An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond.
Chemical ID: MESH:D006861
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rbl2decreases expressionISORBL2 (Homo sapiens)6480464CTDHydrogen Peroxide results in decreased expression of RBL2 mRNAPMID:12419474
Rbl2decreases phosphorylationISORBL2 (Homo sapiens)6480464CTDHydrogen Peroxide results in decreased phosphorylation of RBL2 proteinPMID:12621062
Rbl2increases expressionISORBL2 (Homo sapiens)6480464CTDHydrogen Peroxide results in increased expression of RBL2 mRNAPMID:18951874
Rbl2multiple interactionsISORBL2 (Homo sapiens)6480464CTDcalyculin A inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RBL2 protein]; Okadaic Acid inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of RBL2 protein]PMID:12621062
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