GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | RT1-Bb | decreases expression | EXP | | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of RT1-BB mRNA | PMID:21839799 | RT1-Bb | affects expression | ISO | H2-Ab1 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene affects the expression of HLA-DQB1 mRNA | PMID:22342234 | RT1-Bb | affects methylation | ISO | HLA-DQB1 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene affects the methylation of HLA-DQB1 3' UTR; Benzo(a)pyrene affects the methylation of HLA-DQB1 exon; Benzo(a)pyrene affects the methylation of HLA-DQB1 promoter | PMID:27901495 | RT1-Bb | decreases expression | ISO | H2-Ab1 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in decreased expression of H2-AB1 mRNA | PMID:19770486 PMID:20127859 | RT1-Bb | increases expression | ISO | HLA-DQB1 (Homo sapiens) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of HLA-DQB1 mRNA | PMID:32234424 | RT1-Bb | increases expression | ISO | H2-Ab1 (Mus musculus) | 6480464 | CTD | Benzo(a)pyrene results in increased expression of H2-AB1 mRNA | PMID:21964900 | RT1-Bb | multiple interactions | ISO | H2-Ab1 (Mus musculus) | 6480464 | CTD | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of H2-AB1 mRNA] | PMID:22228805 | |
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