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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3439
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgs1
Name: prostaglandin-endoperoxide synthase 1
Acc ID: CHEBI:32169
Term: Sulpyrine
Definition: An organic molecular entity that has formula C13H16N3O4S.Na.
Chemical ID: MESH:D004177
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs1decreases activityISOPtgs1 (Mus musculus)6480464CTDDipyrone results in decreased activity of PTGS1 proteinPMID:12242329
Ptgs1decreases activityISOPTGS1 (Homo sapiens)6480464CTDDipyrone analog results in decreased activity of PTGS1 protein; Dipyrone results in decreased activity of PTGS1 proteinPMID:16141368
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