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RGD ID: 3438
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgis
Name: prostaglandin I2 synthase
Acc ID: DOID:9001820
Term: Pulmonary Arterial Hypertension
Definition: A progressive rare pulmonary disease characterized by high blood pressure in the PULMONARY ARTERY.
Definition Source(s): MESH:D000081029
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PtgistreatmentIEP 401901264RGD  
PtgissusceptibilityISOPTGIS (Homo sapiens)401959406RGDDNA:repeat, SNPs:promoter, intron: , 185C>T, 325C>A ( , rs5582, rs116939356) (human) 
PtgistreatmentISOPTGIS (Homo sapiens)401901195RGDhuman gene in a rat model 
PtgistreatmentISOPTGIS (Homo sapiens)401959335RGDhuman gene in a rat model 
PtgistreatmentISOPTGIS (Homo sapiens)401959742RGDhuman gene in a rat model 
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