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GENE - TERM ANNOTATION REPORT

RGD ID: 3438
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgis
Name: prostaglandin I2 synthase
Acc ID: DOID:10825
Term: essential hypertension
Definition: A hypertension with no known cause. It is the most common type of hypertension. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Essential_hypertension "DO" "DO", http://www.merckmanuals.com/professional/cardiovascular_disorders/hypertension/overview_of_hypertension.html "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgis ISOPTGIS (Homo sapiens)7240710OMIM  
Ptgis ISOPTGIS (Homo sapiens)11554173CTDCTD Direct Evidence: marker/mechanism 
Ptgis ISOPTGIS (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Essential hypertension | ClinVar Annotator: match by term: Essential hypertension, geneticPMID:12372404 PMID:25741868
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