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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3438
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgis
Name: prostaglandin I2 synthase
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgisaffects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of PTGIS mRNAPMID:22298810
Ptgisdecreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of PTGIS mRNAPMID:11752688 PMID:21215274 PMID:21724226 PMID:32387183
Ptgisincreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in increased expression of PTGIS mRNAPMID:34747641
Ptgisaffects expressionISOPtgis (Mus musculus)6480464CTDTetrachlorodibenzodioxin affects the expression of PTGIS mRNAPMID:21570461
Ptgisdecreases expressionISOPtgis (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in decreased expression of PTGIS mRNAPMID:15591033
Ptgisincreases expressionISOPtgis (Mus musculus)6480464CTDTetrachlorodibenzodioxin results in increased expression of PTGIS mRNAPMID:28213091
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