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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3393
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prkar2a
Name: protein kinase cAMP-dependent type II regulatory subunit alpha
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prkar2aaffects expressionEXP 6480464CTDbisphenol A affects the expression of PRKAR2A mRNAPMID:32145629
Prkar2adecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PRKAR2A mRNAPMID:25181051
Prkar2aincreases expressionEXP 6480464CTDbisphenol A results in increased expression of PRKAR2A mRNAPMID:29097150 PMID:30816183 PMID:32528016
Prkar2adecreases expressionISOPRKAR2A (Homo sapiens)6480464CTDbisphenol A results in decreased expression of PRKAR2A proteinPMID:31675489 PMID:34186270
Prkar2adecreases expressionISOPrkar2a (Mus musculus)6480464CTDbisphenol A results in decreased expression of PRKAR2A mRNAPMID:33221593
Prkar2aincreases expressionISOPRKAR2A (Homo sapiens)6480464CTDbisphenol A results in increased expression of PRKAR2A mRNA; bisphenol A results in increased expression of PRKAR2A proteinPMID:19371625 PMID:37567409
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