GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pparg | affects expression | ISO | PPARG (Homo sapiens) | 6480464 | CTD | 1-Methyl-4-phenylpyridinium affects the expression of PPARG mRNA | PMID:24767308 | Pparg | decreases expression | ISO | PPARG (Homo sapiens) | 6480464 | CTD | 1-Methyl-4-phenylpyridinium results in decreased expression of PPARG protein | PMID:26141122 PMID:30965670 | Pparg | multiple interactions | ISO | PPARG (Homo sapiens) | 6480464 | CTD | [1-Methyl-4-phenylpyridinium co-treated with PPARGC1A protein] results in increased expression of PPARG mRNA; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of PPARG protein]; PPARGC1A protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of PPARG protein]; tideglusib inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of PPARG protein] | PMID:26141122 PMID:30965670 | |
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