GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pparg | multiple interactions | EXP | | 6480464 | CTD | [9-deoxy-delta-9-prostaglandin D2 co-treated with Alitretinoin] promotes the reaction [[PPARG protein binds to RXRA protein] which binds to GSTA2 promoter]; Alitretinoin binds to and results in increased activity of PPARG protein | PMID:15150131 PMID:18063688 | Pparg | increases activity | ISO | PPARG (Homo sapiens) | 6480464 | CTD | Alitretinoin results in increased activity of PPARG protein | PMID:15707588 | Pparg | multiple interactions | ISO | PPARG (Homo sapiens) | 6480464 | CTD | benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Alitretinoin results in increased activity of PPARG protein]; MG 262 promotes the reaction [Alitretinoin results in increased activity of PPARG protein] | PMID:15707588 | Pparg | multiple interactions | ISO | Pparg (Mus musculus) | 6480464 | CTD | [Pioglitazone co-treated with Alitretinoin] inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; PPARG protein promotes the reaction [Alitretinoin results in increased expression of PPARGC1A mRNA] | PMID:16513826 PMID:17019405 | | ||||||||||||||||||||||
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