GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pgr | multiple interactions | EXP | | 6480464 | CTD | [Fulvestrant co-treated with Coumestrol] results in decreased expression of PGR mRNA; Fulvestrant inhibits the reaction [8-prenylnaringenin results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [biochanin A results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [butylparaben results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [butylparaben results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [Cadmium Chloride results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Ethinyl Estradiol results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [isobutylparaben results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [isopropyl 4-hydroxybenzoate results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [isopropyl 4-hydroxybenzoate results in increased expression of PGR protein] | PMID:12858169 PMID:19654335 PMID:23209616 PMID:23211298 PMID:31926947 PMID:34848279 | Pgr | decreases expression | ISO | Pgr (Mus musculus) | 6480464 | CTD | Fulvestrant results in decreased expression of PGR mRNA | PMID:30061528 | Pgr | decreases expression | ISO | PGR (Homo sapiens) | 6480464 | CTD | Fulvestrant results in decreased expression of PGR mRNA; Fulvestrant results in decreased expression of PGR protein | PMID:11867264 PMID:15072547 PMID:20179196 PMID:20206645 PMID:20543978 PMID:26865669 PMID:31646340 | Pgr | multiple interactions | ISO | Pgr (Mus musculus) | 6480464 | CTD | bisphenol A promotes the reaction [Fulvestrant results in decreased expression of PGR mRNA]; Estradiol promotes the reaction [Fulvestrant results in decreased expression of PGR mRNA]; Fulvestrant affects the reaction [Chlordecone results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of PGR mRNA]; Fulvestrant promotes the reaction [Estradiol results in decreased expression of PGR mRNA] | PMID:30061528 PMID:37657410 PMID:9607801 | Pgr | multiple interactions | ISO | PGR (Homo sapiens) | 6480464 | CTD | Fulvestrant binds to and results in decreased activity of PGR protein; Fulvestrant inhibits the reaction [1,7-diphenyl-5-heptene-3-one results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of PGR protein alternative form]; Fulvestrant inhibits the reaction [27-hydroxycholesterol results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [4-hydroxy-equilenin results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [alternariol results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [arsenite results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [bifenthrin results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [bisphenol A analog results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [bisphenol F results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [bisphenol S results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [chromous chloride results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [chromous chloride results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [cobaltous chloride results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [cobaltous chloride results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [cupric chloride results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [cupric chloride results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [CXCL12 protein results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [desmethylicaritin results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Diarylheptanoids results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Diethylstilbestrol results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Estradiol results in decreased expression of PGR protein alternative form]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of PGR protein alternative form]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [Estrogens results in increased expression of PGR protein alternative form]; Fulvestrant inhibits the reaction [Estrone results in decreased expression of PGR protein alternative form]; Fulvestrant inhibits the reaction [gamma-terpinene results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [icariin results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [icaritin results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [isobavachin results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [isobavachin results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [lead chloride results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [lead chloride results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [Limonene results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [linalool results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [linalyl acetate results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Mercuric Chloride results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Mercuric Chloride results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [Mycotoxins results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [nickel chloride results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [nickel chloride results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [o,p'-DDT results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [pentabrominated diphenyl ether 100 results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Tea Tree Oil results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [terpinenol-4 results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Vanadates results in increased expression of PGR mRNA]; Fulvestrant inhibits the reaction [Vanadates results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [zearalenol results in increased expression of PGR protein]; Fulvestrant inhibits the reaction [Zearalenone results in increased expression of PGR protein] | PMID:10411312 PMID:11014213 PMID:11391616 PMID:12746304 PMID:15319301 PMID:15541416 PMID:15806153 PMID:16323292 PMID:16892383 PMID:17872378 PMID:19584281 PMID:19654927 PMID:20206645 PMID:20540524 PMID:21803136 PMID:23665424 PMID:24938463 PMID:25752796 PMID:29389661 PMID:30796839 PMID:31393563 PMID:31646340 PMID:34831106 | |
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